Een doorbraak ontvouwt zich A breakthrough unfolds

In december 2019 loste AlphaFold, het AI-systeem van DeepMind, een grote uitdaging in de biologie op waar al vijftig jaar aan werd gewerkt: het eiwitvouwingsprobleem. Een kop in het tijdschrift Nature luidde: “It will change everything”, en de president van de Britse Royal Society noemde het een “verbluffende vooruitgang [die] decennia eerder kwam dan velen in het vakgebied hadden voorspeld”. In deze aflevering ontdekt Hannah het verhaal achter AlphaFold van de mensen die het mogelijk maakten, en hoe het de toekomst van gezondheidszorg en geneeskunde kan helpen veranderen. Heb je vragen of feedback over de serie? Stuur ons een bericht op Twitter via @DeepMind of mail naar podcast@deepmind.com. Geïnterviewd: Demis Hassabis, John Jumper, Kathryn Tunyasunakool en Sasha Brown van DeepMind; Charles Mowbray en Monique Wasuna van het Drugs for Neglected Diseases initiative (DNDi]) en John McGeehan van het Centre for Enzyme Innovation aan de University of Portsmouth Credits Presentatie: Hannah Fry Serieproducent: Dan Hardoon Productieondersteuning: Jill Achineku Sounddesign: Emma Barnaby Muziek: Eleni Shaw Geluidstechnicus: Nigel Appleton Eindredactie: David Prest In opdracht van DeepMind Dank aan iedereen die dit seizoen mogelijk heeft gemaakt! Verder lezen: AlphaFold-blog, DeepMind: https://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology AlphaFold-casestudy, DeepMind: https://deepmind.com/research/case-studies/alphafold It will change everything, Nature: https://www.nature.com/articles/d41586-020-03348-4 AlphaFold Is The Most Important Achievement In AI—Ever, Forbes: https://www.forbes.com/sites/robtoews/2021/10/03/alphafold-is-the-most-important-achievement-in-ai-ever/?sh=359278426e0a Bacteria found to eat PET plastics, NewScientist: https://www.newscientist.com/article/2080279-bacteria-found-to-eat-pet-plastics-could-help-do-the-recycling/ Protein Structure Prediction Center: https://predictioncenter.org/ Een interview met professor John McGeehan, BBSRC: https://bbsrc.ukri.org/news/features/enzyme-science/an-interview-with-professor-john-mcgeehan/ Profiel van John McGeehan, University of Portsmouth: https://researchportal.port.ac.uk/en/persons/john-mcgeehan Drugs for Neglected Diseases initiative (DNDi): https://dndi.org/ A doctor’s dream, DNDi: https://www.youtube.com/watch?v=Tk31iucWYdE The Curious Cases of Rutherford and Fry, BBC: https://www.bbc.co.uk/programmes/b07dx75g/episodes/downloads Hannah Fry: https://hannahfry.co.uk/ Seizoen 1 en 2 vind je op YouTube: http://dpmd.ai/3geDPmL Of zoek op “DeepMind: The Podcast” en abonneer je in je favoriete podcastapp: Apple Podcasts: http://dpmd.ai/2Rzlmcu Google Podcasts: http://dpmd.ai/3geDjp5 Spotify: http://dpmd.ai/3w29cb4 Pocket Casts: https://pca.st/30m1

In December 2019, DeepMind’s AI system, AlphaFold, solved a 50-year-old grand challenge in biology, known as the protein-folding problem. A headline in the journal Nature read, “It will change everything” and the President of the UK's Royal Society called it a “stunning advance [that arrived] decades before many in the field would have predicted”. In this episode, Hannah uncovers the inside story of AlphaFold from the people who made it happen and finds out how it could help transform the future of healthcare and medicine. For questions or feedback on the series, message us on Twitter @DeepMind or email podcast@deepmind.com. Interviewees: DeepMind’s Demis Hassabis, John Jumper, Kathryn Tunyasunakool and Sasha Brown; Charles Mowbray and Monique Wasuna of the Drugs for Neglected Diseases initiative (DNDi]) & John McGeehan of the Centre for Enzyme Innovation at the University of Portsmouth Credits Presenter: Hannah Fry Series Producer: Dan Hardoon Production support: Jill Achineku Sounds design: Emma Barnaby Music composition: Eleni Shaw Sound Engineer: Nigel Appleton Editor: David Prest Commissioned by DeepMind Thank you to everyone who made this season possible! Further reading: AlphaFold blog, DeepMind: https://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology AlphaFold case study, DeepMind: https://deepmind.com/research/case-studies/alphafold It will change everything, Nature: https://www.nature.com/articles/d41586-020-03348-4 AlphaFold Is The Most Important Achievement In AI—Ever, Forbes: https://www.forbes.com/sites/robtoews/2021/10/03/alphafold-is-the-most-important-achievement-in-ai-ever/?sh=359278426e0a Bacteria found to eat PET plastics, NewScientist: https://www.newscientist.com/article/2080279-bacteria-found-to-eat-pet-plastics-could-help-do-the-recycling/ Protein Structure Prediction Center: https://predictioncenter.org/ An interview with Professor John McGeehan, BBSRC: https://bbsrc.ukri.org/news/features/enzyme-science/an-interview-with-professor-john-mcgeehan/ John McGeehan profile, University of Portsmouth: https://researchportal.port.ac.uk/en/persons/john-mcgeehan Drugs for Neglected Diseases initiative (DNDi): https://dndi.org/ A doctor’s dream, DNDi: https://www.youtube.com/watch?v=Tk31iucWYdE The Curious Cases of Rutherford and Fry, BBC: https://www.bbc.co.uk/programmes/b07dx75g/episodes/downloads Hannah Fry: https://hannahfry.co.uk/ Find Seasons 1 & 2 on YouTube: http://dpmd.ai/3geDPmL Or search “DeepMind: The Podcast” and subscribe on your favourite podcast app: Apple Podcasts: http://dpmd.ai/2Rzlmcu Google Podcasts: http://dpmd.ai/3geDjp5 Spotify: http://dpmd.ai/3w29cb4 Pocket Casts: https://pca.st/30m1